Correlation of corneal epithelial thickness with clinical severity of dry eye

Background: Spectral-domain optical coherence tomography (OCT) has been used to measure corneal epithelium thickness in dry eye disease, allowing assessment of ocular-surface damage different disease severity. Aim: This study aimed determine the characteristics epithelial with spectral-domain OCT patients and correlate clinical Setting: The was conducted at outpatient clinic Department Ophthalmology, Chulabhorn hospital, Bangkok, Thailand. Methods: It a cross-sectional 92 were included. All participants assessed using questionnaire-5 (DEQ-5), tear film breakup time fluorescein staining. Corneal measured OCT. mean variance calculated. Correlations other parameters Results: There no statistical differences between non-severe severe groups. peripheral significantly higher eye. significant correlation parameters. Conclusion: Peripheral eye, suggesting that ocular surface is more damaged. also correlated symptoms signs which can be assess Contribution: provided measurement on diagnosis severities.